人参皂甙 Rg1_化工百科

中文名	人参皂苷 Rg1
英文名	ginsenoside Rg1
别名	三七皂苷C1 人参皂苷Rg1 人参皂荚RG1 人参皂甙 Rg1 人参皂苷 Rg1 人参皂苷RGL(分析标准品) 人参皂苷 RG1 (人参皂素) 人参皂苷RG1(三七皂苷C1) GINSENOSIDE RG1 人参皂苷RG1
英文别名	Panaxoside A Ginsenoside g1 Ginsenoside A2 Panaxoside Rg1 Sanchinoside C1 ginsenoside Rg1 Gensenoside Rg1 Sanchinoside Rg1 Ginsenoside Rg1 std. GINSENOSIDE RG1 WITH HPLC dihydroxydammar-24-ene-6,20-diylbis- (6)-beta-D-Glucopyranosyl-(20)-beta-D-glucopyranosyl-20S-protopanaxatriol (3b,6a,12b)-3,12-dihydroxydammar-24-ene-6,20- diylbis(beta-d-glucopyranoside) (3beta,6alpha,12beta)-3,12-dihydroxydammar-24-ene-6,20-diylbis[beta-D-glucopyranoside] (3beta,6alpha,12beta)-3,12-Dihydroxydammar-24-ene-6,20-diylbis(beta-D-glucopyranoside) (3beta,6alpha,12beta)-3,12-Dihydroxydammar-24-ene-6,20-diyl bis-beta-D-Glucopyranoside beta-D-Glucopyranoside, (3beta,6alpha,12beta)-3,12-dihydroxy dammar-24-ene-6,20-diylbis- beta-D-Glucopyranoside, (3beta,6alpha,12beta)-3,12-dihydroxydammar-24-ene-6,20-diyl bis- (3beta,6alpha,12beta)-20-(beta-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl beta-D-glucopyranoside 2-[6-(hexopyranosyloxy)-3,12-dihydroxy-4,4,7,10,14-pentamethylgonan-17-yl]-6-methylhept-5-en-2-yl hexopyranoside
CAS	22427-39-0
EINECS	244-989-9
化学式	C42H72O14
分子量	801.01
InChI	InChI=1/C42H72O14/c1-20(2)10-9-13-42(8,56-37-34(52)32(50)30(48)25(19-44)55-37)21-11-15-40(6)28(21)22(45)16-26-39(5)14-12-27(46)38(3,4)35(39)23(17-41(26,40)7)53-36-33(51)31(49)29(47)24(18-43)54-36/h10,21-37,43-52H,9,11-19H2,1-8H3/t21-,22+,23-,24+,25+,26+,27-,28-,29+,30+,31-,32-,33+,34+,35-,36+,37-,39+,40+,41+,42-/m0/s1
密度	1.33±0.1 g/cm3(Predicted)
熔点	194～197℃
沸点	898.5±65.0 °C(Predicted)
比旋光度	+32°（pyridine）
闪点	497.2°C
蒸汽压	0mmHg at 25°C
溶解度	DMSO (微溶) 、甲醇 (微溶) 、吡啶 (微溶)
折射率	1.601
酸度系数	12.91±0.70(Predicted)
存储条件	Sealed in dry,Store in freezer, under -20°C
稳定性	吸湿性
外观	整洁
颜色	White to Off-White
物化性质	白色结晶粉末，易溶于甲醇，乙醇，来源于人参、西洋参。
MDL号	MFCD00210293
危险品标志	Xn - 有害物品 T - 有毒物品 F - 易燃物品
风险术语	R22 - 吞食有害。 R39/23/24/25 - R23/24/25 - 吸入、皮肤接触及吞食有毒。 R11 - 高度易燃。
安全术语	S2 - 避免儿童触及。 S45 - 若发生事故或感不适，立即就医(可能的话，出示其标签)。 S36/37 - 穿戴适当的防护服和手套。 S16 - 远离火源。 S7 - 保持容器密封。 S24/25 - 避免与皮肤和眼睛接触。
WGK Germany	3
RTECS	LY9537200
海关编号	29389090
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[IF=1.967] Meijia Li et al."Brain Concentration of Ginsenosides and Pharmacokinetics after Oral Administration of Mountain-cultivated Ginseng."J Chin Chem Soc-Taip. 2017 Apr;64(4):395-403 79. [IF=1.785] Fengyu Li et al."Ginsenoside Rg1 prevents starvation‑induced muscle protein degradation via regulation of AKT/mTOR/FoxO signaling in C2C12 myotubes."Exp Ther Med. 2017 Aug;14(2):1241-1247 80. [IF=6.558] Qingqing Song et al."Binary code, a flexible tool for diagnostic metabolite sequencing of medicinal plants."Anal Chim Acta. 2019 Dec;1088:89 81. [IF=6.06] Zhenzhuo Li et al."Ginsenosides repair UVB-induced skin barrier damage in BALB/c hairless mice and HaCaT keratinocytes."J Ginseng Res. 2021 May;: 82. [IF=5.878] Jianbo Chen et al."Protection by ginseng saponins against cyclophosphamide-induced liver injuries in rats by induction of cytochrome P450 expression and mediation of the l-arginine/nitric oxide pathway based on metabolomics."Phytother Res. 2021 Jun;35(6): 83. 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人参皂甙 Rg1 - 简介

人参皂苷 Rg1 是一种来源于人参的活性成分，属于人参皂苷的一种。它的化学名称是20-O-β-D-葡萄糖基-20(S)-负丹参酮。以下是有关人参皂苷 Rg1 的一些重要性质、用途、制法和安全信息的介绍：

性质：
- 人参皂苷 Rg1 是一种白色或类白色的粉末状物质。
- 它可以溶解在水中，但在有机溶剂中溶解性较差。

用途：
- 它具有抗氧化、抗炎、抗肿瘤和免疫调节等多种生物活性。
- 人参皂苷 Rg1 被认为对改善认知功能、预防老年痴呆症和心脑血管疾病具有保护作用。
- 它还被用于提高体力、抗疲劳以及增强人体免疫力。

制法：
- 人参皂苷 Rg1 主要从人参中提取。
- 提取方法一般采用水煎浸提、醇沉、浓缩等工艺。
- 提取得到的人参皂苷 Rg1 结晶经过纯化和干燥即可得到纯品。

安全信息：
- 人参皂苷 Rg1 是一种天然成分，一般认为具有较好的安全性。
- 目前尚无明确的毒性报告或副作用报告。
- 使用过程中，应根据医嘱和适当剂量使用。

最后更新：2024-04-09 15:16:49

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